Collection of 12 putative THAP finger human TFs out of 12 considered proteins
DBD Alignment (Click to open/enlarge)
No Structure and Description available
| Ensembl ID | HGNC symbol | DBD Family | Is TF? | TF Assessment | Binding Mode | Motif Status | Notes | Comments |
|---|---|---|---|---|---|---|---|---|
| THAP1 | THAP finger | Yes | Known motif | 1 Monomer or homomultimer | In vivo/Misc source | Likely binds as a homodimer | ||
| THAP10 | THAP finger | Yes | Likely to be sequence specific TF | 1 Monomer or homomultimer | No motif | Paralog THAP1 binds DNA in a sequence specific manner | ||
| THAP11 | THAP finger | Yes | Likely to be sequence specific TF | 1 Monomer or homomultimer | No motif | (PMID: 26876175) has a ChIP-seq motif with GGGARWTGTAGT consensus. THAP11 is an atypical zinc-finger paralogous to THAP1, which has a crystal structure (PDB: 2KO0) where the protein contacts bases TGGGCA | ||
| THAP12 | THAP finger | Yes | Known motif | 1 Monomer or homomultimer | High-throughput in vitro | |||
| THAP2 | THAP finger | Yes | Likely to be sequence specific TF | 1 Monomer or homomultimer | No motif | |||
| THAP3 | THAP finger | Yes | Likely to be sequence specific TF | 1 Monomer or homomultimer | No motif | |||
| THAP4 | THAP finger | Yes | Likely to be sequence specific TF | 1 Monomer or homomultimer | No motif | |||
| THAP5 | THAP finger | Yes | Likely to be sequence specific TF | 1 Monomer or homomultimer | No motif | |||
| THAP6 | THAP finger | Yes | Likely to be sequence specific TF | 1 Monomer or homomultimer | No motif | |||
| THAP7 | THAP finger | Yes | Likely to be sequence specific TF | 1 Monomer or homomultimer | No motif | |||
| THAP8 | THAP finger | Yes | Likely to be sequence specific TF | 1 Monomer or homomultimer | No motif | |||
| THAP9 | THAP finger | Yes | Likely to be sequence specific TF | 1 Monomer or homomultimer | No motif | Human THAP9 Gene Encodes an Active P-Element DNA Transposase (PMID: 23349291) |