Collection of 4 putative TEA human TFs out of 5 considered proteins
DBD Alignment (Click to open/enlarge)
| Description |
Structure |
| Ensembl ID | HGNC symbol | DBD Family | Is TF? | TF Assessment | Binding Mode | Motif Status | Notes | Comments |
|---|---|---|---|---|---|---|---|---|
| APOA4 | TEA | No | Unlikely to be sequence specific TF | 4 Not a DNA binding protein | No motif | APOA4 is Apolipoprotein A4. It consists entirely of Apolipoprotein A1/A4/E domains. The protein product is excluded from the nucleus. I cant see that it has a TEA domain. I believe it is likely to be a low-scoring domain match that almost certainly overlaps with a known domain related to its function as an enzyme. Thus it is unlikely to be a DNA binding protein. | ||
| TEAD1 | TEA | Yes | Known motif | 1 Monomer or homomultimer | High-throughput in vitro | |||
| TEAD2 | TEA | Yes | Known motif | 1 Monomer or homomultimer | High-throughput in vitro | |||
| TEAD3 | TEA | Yes | Known motif | 1 Monomer or homomultimer | High-throughput in vitro | |||
| TEAD4 | TEA | Yes | Known motif | 1 Monomer or homomultimer | High-throughput in vitro |