Collection of 5 putative CSD human TFs out of 8 considered proteins

DBD Alignment (Click to open/enlarge)


Click to download Alignment and Tree
No Structure and Description available
Ensembl ID HGNC symbol DBD Family Is TF? TF Assessment Binding Mode Motif Status Notes Comments
CARHSP1 CSD No ssDNA/RNA binding 4 Not a DNA binding protein No motif RNA-binding protein (PMID: 11842224; PMID: 21078874)
CSDC2 CSD No ssDNA/RNA binding 4 Not a DNA binding protein No motif RNA-binding protein (PMID: 12801884)
CSDE1 CSD No ssDNA/RNA binding 4 Not a DNA binding protein No motif Established RNA-binding protein.
LIN28A CSD Yes Inferred motif 1 Monomer or homomultimer High-throughput in vitro Might also bind RNA
LIN28B CSD Yes Known motif 1 Monomer or homomultimer High-throughput in vitro Structure (PDB: 4A75) is with single stranded DNA.
YBX1 CSD Yes Known motif 1 Monomer or homomultimer High-throughput in vitro Might also bind RNA
YBX2 CSD Yes Inferred motif 1 Monomer or homomultimer High-throughput in vitro Might also bind RNA
YBX3 CSD Yes Known motif 1 Monomer or homomultimer 100 perc ID - in vitro Identical DBD to YBX1. Might also bind RNA.