Collection of 3 putative CCCH ZF human TFs out of 43 considered proteins
DBD Alignment (Click to open/enlarge)
No Structure and Description available
| Ensembl ID | HGNC symbol | DBD Family | Is TF? | TF Assessment | Binding Mode | Motif Status | Notes | Comments |
|---|---|---|---|---|---|---|---|---|
| CPSF4 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| CPSF4L | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| DHX57 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| DUS3L | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| HELZ | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| MBNL1 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| MBNL2 | CCCH ZF | Yes | Likely to be sequence specific TF | 1 Monomer or homomultimer | High-throughput in vitro | Has methylated and unmethylated HT-SELEX motifs, despite this family largely binding RNA exclusively (PMID: 28473536 ) | ||
| MBNL3 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| MKRN1 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| MKRN2 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| NUPL2 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| PARP12 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | Likely an RNA binding protein (PMID: 25086041). | ||
| PPP1R10 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | Close ortholog (PP1RA) binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers (Uniprot). | ||
| PRR3 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| RC3H1 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | A well established RNA-binding protein reviewed in (PMID: 26489670). | ||
| RC3H2 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| RNF113A | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| RNF113B | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| TOE1 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| TRMT1 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| UNK | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| UNKL | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| ZC3H10 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| ZC3H11A | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| ZC3H12A | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| ZC3H13 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| ZC3H14 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | Binds UUUNUUU RNA-sequence based on Ray et al 2013 (PMID: 23846655). | ||
| ZC3H15 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| ZC3H18 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| ZC3H3 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| ZC3H4 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | Has a putative AT-hook | ||
| ZC3H6 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| ZC3H7A | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| ZC3H7B | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| ZC3H8 | CCCH ZF | Yes | Likely to be sequence specific TF | 1 Monomer or homomultimer | No motif | Mouse ortholog can bind DNA specifically, based on EMSA (PMID: 12077251). | ||
| ZC3HAV1 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | RNA-binding protein (PMID: 22658674; PMID: 22681889). | ||
| ZFP36 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | RNA binding protein (PMID: 10330172). | ||
| ZFP36L1 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | RNA-binding protein (PMID: 27102483; PMID: 17013884). | ||
| ZFP36L2 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | RNA-binding protein (PMID: 20506496). | ||
| ZGPAT | CCCH ZF | Yes | Likely to be sequence specific TF | 1 Monomer or homomultimer | No motif | Binds RRRGGAGGAGA based on SELEX and EMSA (PMID: 19644445). | ||
| ZMAT5 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| ZRSR1 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif | |||
| ZRSR2 | CCCH ZF | No | ssDNA/RNA binding | 4 Not a DNA binding protein | No motif |