| AC008770.3 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| AC092835.1 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
KRAB C2H2 Protein |
| AC138696.1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
100 perc ID - in vitro |
|
|
| AEBP2 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| AKAP8 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
(PMID: 26683827) uses SELEX to show binding to G/C rich DNA, and confirms association with rDNA promoters. Also claims it has a C2H2 domain. Interpro says it has a C2H2 AKAP95-type 1 and a C2H2 AKAP95-type 2 domain. SMART does identify a single C2H2 domain. |
| AKAP8L |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
This is homologous to the AKAP8/AKAP95 protein. which has been shown by SELEX to bind GC rich sequences (PMID: 26683827). |
| ANKZF1 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
|
| ATMIN |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| BCL11A |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| BCL11B |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| BCL6 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| BCL6B |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| BNC1 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| BNC2 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Has a putative AT-hook |
|
| CASZ1 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| CCDC17 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
|
| CHAMP1 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
|
| CPXCR1 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
|
| CTCF |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
Has a putative AT-hook |
|
| CTCFL |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| DPF1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
This protein contains C2H2 ZFs missed by Pfam scanning. |
| DPF3 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
High-throughput in vitro |
Single C2H2 domain |
Single C2H2 ZF. PHD domains mediate recognition of acetylated histones (PMID: 20613843); unclear if the ZF contributes DNA-binding specificity to the interaction. |
| DZIP1 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain; Has a putative AT-hook |
|
| E4F1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| EEA1 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
Based on (PMID: 20534488), the protein has a C2H2 ZF domain; but it uses the domain for contacting RAB5A rather than for binding DNA. |
| EGR1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| EGR2 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
Binds HOX4A promoter (PMID:21836637) |
| EGR3 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| EGR4 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| FAM170A |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
Degenerate C2H2-ZFP. Localizes to the nucleus and overexpression upregulates other genes (PMID: 20162441). |
| FEZF1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| FEZF2 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| FIZ1 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Protein has a decent cassette of C2H2 ZF domains (not all are detected by Pfam). It has been also shown to interact with homeodomain protein CRX (PMID: 18854042) and MAF-subtype bZIP protein NRL (PMID: 12566383). |
| GFI1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| GFI1B |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| GLI1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| GLI2 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| GLI3 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| GLI4 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Motif obtained from MEME - not supported by recognition code (RCADE) and may be inaccurate or indirect |
Protein is not closely homologous to GLI1-3 proteins. |
| GLIS1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| GLIS2 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| GLIS3 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| GTF3A |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| GZF1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| HIC1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| HIC2 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| HINFP |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| HIVEP1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| HIVEP2 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| HIVEP3 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Has a putative AT-hook |
Binds to NFKB-like consensus sequence to repress transcription (PMID: 21189157). PWMs for HIVEP1 and 2 in Transfac and Hocomoco are also NFKB-like. |
| IKZF1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| IKZF2 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| IKZF3 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| IKZF4 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| IKZF5 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| INSM1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| INSM2 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| JAZF1 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| KAT7 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| KCMF1 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
No evidence of DNA-binding in the literature; and has evidence of E3 ligase activity (PMID:15581609). |
| KIN |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
Binds curved DNA (PMID: 8078469). |
| KLF1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| KLF10 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| KLF11 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| KLF12 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| KLF13 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| KLF14 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| KLF15 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| KLF16 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| KLF17 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| KLF2 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| KLF3 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| KLF4 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| KLF5 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
Binds as a monomer and as a dimer (PMID: 25575120). |
| KLF6 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| KLF7 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
100 perc ID - in vitro |
Motif obtained from MEME - not supported by recognition code (RCADE) and may be inaccurate or indirect |
|
| KLF8 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
100 perc ID - in vitro |
|
|
| KLF9 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
100 perc ID - in vitro |
|
|
| L3MBTL1 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Histone modifier; polycomb protein. |
| L3MBTL3 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Histone modifier; polycomb protein. |
| L3MBTL4 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Histone modifier; polycomb protein. |
| MAZ |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| MECOM |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| MTF1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| MYNN |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| MYT1 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Crystal structure (PDB:2JX1) has GTGAACTTTCGGT DNA; similar to MYT1L SELEX and PBM sites. |
| MYT1L |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| MZF1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| OSR1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| OSR2 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| OVOL1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| OVOL2 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| OVOL3 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| PEG3 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
SCAN C2H2 ZF Protein. |
| PLAG1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| PLAGL1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| PLAGL2 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| PRDM1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| PRDM10 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Has a putative AT-hook |
|
| PRDM12 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| PRDM13 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| PRDM14 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| PRDM15 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| PRDM16 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| PRDM2 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Has been suggested to function as a histone methyltransferase (PMID: 15282304), but it has a decent set of C2H2 ZF domains and could thus bind DNA independently. |
| PRDM4 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| PRDM5 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Has a nice cassette of C2H2 ZF domains. Moreover, (PMID: 17636019) has performed SELEX for it and validated the result. |
| PRDM6 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Motif obtained from MEME - not supported by recognition code (RCADE) and may be inaccurate or indirect |
|
| PRDM8 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| PRMT3 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
Has a single C2H2 ZF (PMID: 10931850). |
| RBSN |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
Potential false positive - protein functions in membrane trafficking. |
| REPIN1 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Binds DNA specifically based on EMSA and nuclease footprinting (PMID: 10606657). |
| REST |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| RLF |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| RREB1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| SALL1 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| SALL2 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| SALL3 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| SALL4 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| SCRT1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| SCRT2 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| SLC2A4RG |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
Two papers demonstrate a bit of evidence for DNA binding (PMID:10825161 and PMID: 14625278 ). |
| SNAI1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| SNAI2 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| SNAI3 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| SP1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| SP2 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| SP3 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| SP4 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| SP5 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
Transfac motif has some similarity to known Sp1 TF motifs from multiple species and sources |
| SP6 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| SP7 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| SP8 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| SP9 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ST18 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| TRAFD1 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
Possible false positive: the protein negatively regulates IRF3 and NFKB but there is no evidence for DNA-binding and it is likely to operate upstream on the signalling cascade (PMID:18849341). |
| TSHZ1 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| TSHZ2 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Also contains an atypical homodomain (Uniprot) not identified by Pfam. |
| TSHZ3 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
The C2H2 domains are too spread out to be credible; but there is also a homodomain. Seems more likely than not that it binds DNA. |
| VEZF1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| WIZ |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Has a putative AT-hook |
Regulates the G9aGLP complex for gene repression; has a ChIP-seq derived DNA-binding motif (PMID:25789554). |
| WT1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
Crystal structure (PDB:2JP9) is with dsDNA GCGCAGACGCCCCCGCG, which is consistent with the PWMs |
| YY1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| YY2 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZBTB1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
100 perc ID - in vitro |
|
|
| ZBTB10 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains and a BTB homodimerization domain |
| ZBTB11 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| ZBTB12 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZBTB14 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZBTB16 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| ZBTB17 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZBTB18 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZBTB2 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZBTB20 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZBTB21 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains and a BTB homodimerization domain |
| ZBTB22 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZBTB25 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZBTB26 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZBTB3 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
100 perc ID - in vitro |
|
|
| ZBTB32 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZBTB33 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| ZBTB34 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZBTB37 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZBTB38 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
It has a decent cassette of znfC2H2 domains and a BTB homodimerization domain. Requires CpG methylation for binding into a site in MYOG-promoter (PMID: 21625269). |
| ZBTB39 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZBTB4 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| ZBTB40 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains and a BTB homodimerization domain |
| ZBTB41 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZBTB42 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZBTB43 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZBTB44 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZBTB45 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZBTB46 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Specificity is unknown; functions in dendritic cells (PMID: 22615130). |
| ZBTB47 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZBTB48 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Motif obtained from MEME - not supported by recognition code (RCADE) and may be inaccurate or indirect |
|
| ZBTB49 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZBTB5 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
Binds to GATCGGGCGGGGCGGTTGTATATCA; GATCCGTTAGAGGAAGAAGACTGGGCATGTCTG and GATCCATCAGGAACATGTCCCAACATGTTGAGCTC based on EMSA using recombinant protein (PMID: 19491398). |
| ZBTB6 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Motif obtained from MEME - not supported by recognition code (RCADE) and may be inaccurate or indirect |
|
| ZBTB7A |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZBTB7B |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZBTB7C |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZBTB8A |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a two znfC2H2 domains and a BTB-domain |
| ZBTB8B |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains and a BTB homodimerization domain |
| ZBTB9 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has two znfC2H2 domains and a BTB-domain that typically mediates homotypic dimerization |
| ZFAT |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Has a putative AT-hook |
|
| ZFP2 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| ZFP3 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZFP41 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZFP42 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZFP62 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains |
| ZFP64 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Motif obtained from MEME - not supported by recognition code (RCADE) and may be inaccurate or indirect |
|
| ZFP91 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Possible false positive. An Atypical E3 ubiquitin-protein ligase that mediates Lys-63-linked ubiquitination of MAP3K14/NIK; leading to stabilization and activation of MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway (PMID: 20682767). |
| ZFPM1 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZFPM2 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
FOG-proteins use some of their zinc-fingers to interact with the GATA proteins. Other C2H2 ZFs are probably also capable of binding DNA (PMID: 10329627). |
| ZFX |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| ZFY |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| ZIC1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZIC2 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
100 perc ID - in vitro |
|
|
| ZIC3 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZIC4 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZIC5 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZMAT1 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
Possible RBP. |
| ZMAT4 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Possible RBP. |
| ZNF107 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains and a KRAB-domain |
| ZNF117 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| ZNF121 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF131 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Evidence for DNA binding (PMID: 20303951 ). |
| ZNF134 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF138 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF142 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF143 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF146 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF148 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| ZNF16 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF165 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains and a SCAN-domain and that it appears to be expressed commonly in urinary bladder cancers PMID: 25214475 |
| ZNF174 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF200 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF207 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF217 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
Based on (PDB: 3UK3) this protein has at least two DNA binding znf domains. In vitro evidence for DNA binding (PMID:17130829). |
| ZNF219 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
Binds CCCCCA based on SELEX (PMID: 14621294). |
| ZNF22 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF221 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF232 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF236 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| ZNF239 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Binds TAAAGGCT based on EMSA (PMID: 11278819). |
| ZNF24 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF260 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF275 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF276 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF280A |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Motif obtained from MEME - not supported by recognition code (RCADE) and may be inaccurate or indirect |
|
| ZNF280B |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF280C |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF280D |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF281 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF286B |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains |
| ZNF292 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF296 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF318 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Possible RNA-binding protein; it has two u1 type ZNF domains (PMID: 25057009). |
| ZNF319 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains |
| ZNF32 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF322 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF326 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
ZNF326 is a member of the DBIRD complex that regulates splicing by binding to PolII in an RNA-independant manner (PMID:22446626). |
| ZNF329 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF335 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Has a putative AT-hook |
|
| ZNF341 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Motif obtained from MEME - not supported by recognition code (RCADE) and may be inaccurate or indirect |
|
| ZNF345 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF346 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Binds dsDNA with low affinity and no discernible specificity (PMID: 24521053). |
| ZNF35 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF358 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF362 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains |
| ZNF365 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
Also contains a Ku C terminal like domain that is thought to be involved in DNA-damage repair pathways. |
| ZNF366 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
This protein has been shown to complex with and function as a corepressor for ESR1 (PMID: 17085477) and glucocorticoid receptor (PMID: 23440419). It has a nice set of znfs and could thus well bind DNA independently. |
| ZNF367 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Has a putative AT-hook |
Virtually nothing is known for this protein except that it has two znfC2H2 domains next to each other |
| ZNF384 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF385A |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF385B |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF385C |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF385D |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF391 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF395 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
Contains a single ZF (string matching on Uniprot) that is not identified using Pfam HMM thresholds. Shown to bind a short DNA sequence (GCCGGCG) by EMSA and DNase I footprinting (PMID:14625278). |
| ZNF396 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF397 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains and that it binds on centromeric regions PMID: 18369653 |
| ZNF407 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Has a putative AT-hook |
Protein has a decent cassette of znfC2H2 domains; a study links it in regulation of glucose intake receptor GLUT4 (PMID: 25596527). |
| ZNF408 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF410 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF414 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Its on the low end of confidence that its a TF; since most of the domains are variants of C2H2; but its more likely than not since they are in a row. |
| ZNF415 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Motif obtained from MEME - not supported by recognition code (RCADE) and may be inaccurate or indirect |
|
| ZNF423 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| ZNF428 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
|
| ZNF438 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has two znfC2H2 domains and that it represses transcription in a reporter assay PMID: 17669267 |
| ZNF444 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF449 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF451 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF462 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Has many znfC2H2 like domains that are however not in tight arrays but interspersed throughout the sequence |
| ZNF467 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF469 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Has a putative AT-hook |
|
| ZNF474 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
|
| ZNF48 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF488 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has two znfC2H2 domains |
| ZNF491 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains |
| ZNF493 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF497 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF501 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF502 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF503 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
|
| ZNF507 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF511 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF512B |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Has a putative AT-hook |
Protein has znfC2H2 domains but they are fragmented rather than making decent cassettes |
| ZNF513 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF516 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF518A |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains and that it interacts with polycomb repressor complex 2 PMID: 25680957 |
| ZNF518B |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF521 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| ZNF525 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF526 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains |
| ZNF532 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has decent cassettes of znfC2H2 domains |
| ZNF536 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF572 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains |
| ZNF574 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF575 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF576 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF579 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF580 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF581 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| ZNF592 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF594 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF595 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF598 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF600 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF608 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
|
| ZNF609 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
|
| ZNF618 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF619 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Motif obtained from MEME - not supported by recognition code (RCADE) and may be inaccurate or indirect |
|
| ZNF623 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF625 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains and a KRAB-domain |
| ZNF628 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains. The transfac model doesnt look like a common suspect |
| ZNF629 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF639 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Promotes transcription of HIV genes (PMID: 24204263). |
| ZNF644 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Possible false positive. Arrangement of C2H2 domains seems inconsistent with DNA binding. |
| ZNF645 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
|
| ZNF646 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains |
| ZNF648 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF652 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF654 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF655 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains |
| ZNF66 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF660 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF664 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| ZNF665 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF668 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF670 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Has a nice cassette of znfC2H2 domains and a KRAB domain |
| ZNF672 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains |
| ZNF678 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF683 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF687 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF691 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF692 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Motif obtained from MEME - not supported by recognition code (RCADE) and may be inaccurate or indirect |
|
| ZNF696 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF697 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| ZNF70 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF703 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
|
| ZNF704 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
Single C2H2 domain |
|
| ZNF705E |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Has a nice cassette of znfC2H2 domains and a KRAB domain |
| ZNF706 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
|
| ZNF708 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF71 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF710 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known about this protein except that it has a nice array of znfC2H2 domains |
| ZNF711 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
|
|
| ZNF718 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| ZNF721 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains and a KRAB-domain |
| ZNF740 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF750 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain; Has a putative AT-hook |
Influences KLF4 expression (PMID: 22364861). |
| ZNF76 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF761 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| ZNF768 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZNF770 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Motif obtained from MEME - not supported by recognition code (RCADE) and may be inaccurate or indirect |
|
| ZNF771 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF775 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains and a MBD domain |
| ZNF781 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF784 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF787 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF788 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains |
| ZNF80 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains. |
| ZNF800 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
C2H2 domains are not arranged in the stereotypic array fashion; but there are several of them. |
| ZNF804A |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
|
| ZNF804B |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
Jaz domain suggests RNA-binding activity |
| ZNF821 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZNF827 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Has been shown to operate on telomeres and recruit the NuRD complex into them (PMID: 25150861). |
| ZNF83 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains |
| ZNF830 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
Possible false positive. The C2H2 domain is a weak match, and doesnt come up on SMART or PFAM. Mouse ortholog is involved in DNA replication and repair (PMID: 25168238; PMID: 21191184). |
| ZNF831 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF835 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains |
| ZNF837 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Has a nice cassette of znfC2H2 domains; virtually nothing is known about it otherwise. |
| ZNF841 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains and a KRAB-domain |
| ZNF843 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
Single C2H2 domain |
|
| ZNF853 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains |
| ZNF865 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZNF883 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| ZNF888 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
One transcript is protein-coding |
| ZSCAN1 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZSCAN10 |
C2H2 ZF(non-KRAB) |
Yes |
Inferred motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZSCAN12 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains and a SCAN-domain |
| ZSCAN16 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZSCAN18 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZSCAN2 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains and a SCAN-domain |
| ZSCAN20 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZSCAN21 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Binds AGYACNNNNNNNGGYAC consensus based on SELEX (PMID: 8625807). |
| ZSCAN22 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZSCAN23 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZSCAN25 |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains and a SCAN-domain |
| ZSCAN26 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
In vivo/Misc source |
Only known motifs are from Transfac or HocoMoco - origin is uncertain |
|
| ZSCAN29 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
Has a putative AT-hook |
|
| ZSCAN30 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZSCAN31 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
Also known as ZNF323 |
| ZSCAN4 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZSCAN5A |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZSCAN5B |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZSCAN5C |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
ChIP-seq motif is consistent with recognition code (RCADE) |
|
| ZSCAN9 |
C2H2 ZF(non-KRAB) |
Yes |
Known motif |
1 Monomer or homomultimer |
High-throughput in vitro |
|
|
| ZUFSP |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZXDA |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
Complexes with CIITA and the similar protein ZXDC to regulate MHCII complex transcription (PMID: 17493635). |
| ZXDB |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|
| ZXDC |
C2H2 ZF(non-KRAB) |
Yes |
Likely to be sequence specific TF |
1 Monomer or homomultimer |
No motif |
|
|