Collection of 6 putative ARID/BRIGHT human TFs out of 14 considered proteins

No Alignment available for ARID_BRIGHT
Ensembl ID HGNC symbol DBD Family Is TF? TF Assessment Binding Mode Motif Status Notes Comments
ARID1A ARID/BRIGHT No Unlikely to be sequence specific TF 3 Low specificity DNA-binding protein No motif Non-specific DNA binder (PMID: 15170388).
ARID1B ARID/BRIGHT No Unlikely to be sequence specific TF 3 Low specificity DNA-binding protein No motif Non-specific DNA binder (PMID: 15170388).
ARID3A ARID/BRIGHT Yes Known motif 1 Monomer or homomultimer 100 perc ID - in vitro
ARID3B ARID/BRIGHT Yes Inferred motif 1 Monomer or homomultimer High-throughput in vitro
ARID3C ARID/BRIGHT Yes Inferred motif 1 Monomer or homomultimer High-throughput in vitro
ARID4A ARID/BRIGHT No Unlikely to be sequence specific TF 3 Low specificity DNA-binding protein No motif Has a putative AT-hook Binds DNA in a sequence non-specific manner (PMID: 15640446).
ARID4B ARID/BRIGHT No Unlikely to be sequence specific TF 3 Low specificity DNA-binding protein No motif Binds DNA in a sequence non-specific manner (PMID: 15640446).
ARID5A ARID/BRIGHT Yes Known motif 1 Monomer or homomultimer 100 perc ID - in vitro
ARID5B ARID/BRIGHT Yes Known motif 1 Monomer or homomultimer 100 perc ID - in vitro Has a putative AT-hook
JARID2 ARID/BRIGHT No Unlikely to be sequence specific TF 3 Low specificity DNA-binding protein No motif Only ARID3 and ARID5 family members have sequence specificity (PMID: 15640446).
KDM5A ARID/BRIGHT No Unlikely to be sequence specific TF 3 Low specificity DNA-binding protein No motif
KDM5B ARID/BRIGHT Yes Likely to be sequence specific TF 1 Monomer or homomultimer No motif Binds GC-rich sequences such as CCGCCC (PMID: 18270511).
KDM5C ARID/BRIGHT No Unlikely to be sequence specific TF 3 Low specificity DNA-binding protein No motif
KDM5D ARID/BRIGHT No Unlikely to be sequence specific TF 3 Low specificity DNA-binding protein No motif Polycomb protein that is well-documented to bind histone marks (PMID: 27477906; PMID: 17351630; PMID: 17320160; PMID: 17320162).