zinc finger protein 460 [Source:HGNC Symbol;Acc:HGNC:21628]
Entrez Summary
Zinc finger proteins, such as ZNF272, interact with nucleic acids
and have diverse functions. The zinc finger domain is a conserved amino acid
sequence motif containing 2 specifically positioned cysteines and 2
histidines that are involved in coordinating zinc. Kruppel-related proteins
form 1 family of zinc finger proteins. See ZFP93 (MIM 604749) for additional
information on zinc finger proteins.[supplied by OMIM, May 2004]
Vaquerizas 2009 TF classification
"a" Has direct evidence of TF function;
"b" Has evidence for an orthologous TF;
"c" contains likely DBDs, but has no functional evidence;
"x" is an unlikely TF such as predicted gene, genes with likely non-specific DBDs or that have function outside transcription;
"other" category contains proteins without clear DBDs they curated from external sources.
b
CisBP considers it as a TF?
Yes
TFclass considers it as a TF?
Yes
Has GO:0003700 "transcription factor activity, sequence-specific DNA binding"
No
GO-Info
Initial Assessment 1a1 Protein has a high confidence PWM (HT-SELEX, PBM or B1H model) or there is a crystal structure that supports sequence specific DNA binding;
1a2 There is high confidence data for a close ortholog (as defined in CisBP);
2a1 There is lower confidence direct evidence, such as a Jaspar, Hocomoco or Transfac model;
2a2 There is lower confidence evidence for an close ortholog;
3a There is decent circumstantial evidence for its role as a TF or not;
4a Two or more datasets predict it as a TF;
5a One of the source datasets predicts is as a TF