ChIP-seq motif is consistent with recognition code (RCADE)
Description
Description:
zinc finger protein 75D [Source:HGNC Symbol;Acc:HGNC:13145]
Entrez Summary
This gene encodes a protein that likely functions as a
transcription factor. The protein, which belongs to the ZNF75 family,
includes an N-terminal SCAN domain, a KRAB box, and five C2H2-type zinc
finger motifs. Another functional gene belonging to this family is located on
chromosome 16, while pseudogenes have been identified on chromosomes 11 and
12. Alternative splicing results in multiple transcripts variants. [provided
by RefSeq, Jun 2010]
Vaquerizas 2009 TF classification
"a" Has direct evidence of TF function;
"b" Has evidence for an orthologous TF;
"c" contains likely DBDs, but has no functional evidence;
"x" is an unlikely TF such as predicted gene, genes with likely non-specific DBDs or that have function outside transcription;
"other" category contains proteins without clear DBDs they curated from external sources.
b
CisBP considers it as a TF?
Yes
TFclass considers it as a TF?
Yes
Has GO:0003700 "transcription factor activity, sequence-specific DNA binding"
Yes
GO-Info
GO:0003700 sequence-specific DNA binding transcription factor activity IBA - GO_REF:0000033
Initial Assessment 1a1 Protein has a high confidence PWM (HT-SELEX, PBM or B1H model) or there is a crystal structure that supports sequence specific DNA binding;
1a2 There is high confidence data for a close ortholog (as defined in CisBP);
2a1 There is lower confidence direct evidence, such as a Jaspar, Hocomoco or Transfac model;
2a2 There is lower confidence evidence for an close ortholog;
3a There is decent circumstantial evidence for its role as a TF or not;
4a Two or more datasets predict it as a TF;
5a One of the source datasets predicts is as a TF