Collection of 4 putative GTF2I-like human TFs out of 4 considered proteins
DBD Alignment (Click to open/enlarge)
No Structure and Description available
| Ensembl ID | HGNC symbol | DBD Family | Is TF? | TF Assessment | Binding Mode | Motif Status | Notes | Comments |
|---|---|---|---|---|---|---|---|---|
| GTF2I | GTF2I-like | Yes | Known motif | 1 Monomer or homomultimer | In vivo/Misc source | Only known motifs are from Transfac or HocoMoco - origin is uncertain | (PMID: 18326499) shows through SELEX and EMSA that this family binds DNA specifically. Transfac motifs are dubious. | |
| GTF2IRD1 | GTF2I-like | Yes | Known motif | 1 Monomer or homomultimer | In vivo/Misc source | Only known motifs are from Transfac or HocoMoco - origin is uncertain | (PMID: 18326499) shows through SELEX and EMSA that this family binds DNA specifically. Transfac motifs are dubious. V$BEN_02 motif has partial similarity to a shift-experiment sequence (PMID:14645227), which shows DNA-binding and evidence of transcriptional regulation by knockdown experiments | |
| GTF2IRD2 | GTF2I-like | Yes | Likely to be sequence specific TF | 1 Monomer or homomultimer | No motif | (PMID: 18326499) shows through SELEX and EMSA that this family binds DNA specifically. | ||
| GTF2IRD2B | GTF2I-like | Yes | Likely to be sequence specific TF | 1 Monomer or homomultimer | No motif | (PMID: 18326499) shows through SELEX and EMSA that this family binds DNA specifically. |