Collection of 5 putative AP-2 human TFs out of 5 considered proteins

DBD Alignment (Click to open/enlarge)


Click to download Alignment and Tree
No Structure and Description available
Ensembl ID HGNC symbol DBD Family Is TF? TF Assessment Binding Mode Motif Status Notes Comments
TFAP2A AP-2 Yes Known motif 1 Monomer or homomultimer High-throughput in vitro
TFAP2B AP-2 Yes Known motif 1 Monomer or homomultimer High-throughput in vitro
TFAP2C AP-2 Yes Known motif 1 Monomer or homomultimer High-throughput in vitro
TFAP2D AP-2 Yes Known motif 1 Monomer or homomultimer In vivo/Misc source Only known motifs are from Transfac or HocoMoco - origin is uncertain Binds the same GCCTGAGGC sequence as the other AP-2s (PMID: 24789576)
TFAP2E AP-2 Yes Known motif 1 Monomer or homomultimer High-throughput in vitro